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| COG2827 | |
|---|---|
 Consensus secondary structure and sequence conservation of COG2827 RNA | |
| Identifiers | |
| Symbol | COG2827 |
| Rfam | RF02938 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
The COG2827 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] COG2827 motifs are found in Clostridiales.
It is ambiguous whether COG2827 RNAs function as cis-regulatory elements or whether they operate in trans. Most COG2827 RNAs occur upstream of genes encoding GIY-YIG endonucleases. Although these genes are often located inside self-splicing introns, the COG2827 RNA motif is much smaller and simpler than known self-splicing introns, and is therefore unlikely to function as a ribozyme.
- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.