CXCR4

CXCR4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS, C-X-C motif chemokine receptor 4, WHIMS1
External IDsOMIM: 162643; MGI: 109563; HomoloGene: 20739; GeneCards: CXCR4; OMA:CXCR4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003467
NM_001008540
NM_001348056
NM_001348059
NM_001348060

NM_009911
NM_001356509

RefSeq (protein)

NP_001008540
NP_003458
NP_001334985
NP_001334988
NP_001334989

NP_034041
NP_001343438

Location (UCSC)Chr 2: 136.11 – 136.12 MbChr 1: 128.52 – 128.52 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

C-X-C chemokine receptor type 4 (CXCR-4) also known as fusin or CD184 (cluster of differentiation 184) is a protein that in humans is encoded by the CXCR4 gene.[5][6] The protein is a CXC chemokine receptor.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000121966Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045382Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Moriuchi M, Moriuchi H, Turner W, Fauci AS (November 1997). "Cloning and analysis of The sigma gene the promoter region of CXCR4, a coreceptor for HIV-1 entry". Journal of Immunology. 159 (9): 4322–9. doi:10.4049/jimmunol.159.9.4322. PMID 9379028. S2CID 36552134.
  6. ^ Caruz A, Samsom M, Alonso JM, Alcami J, Baleux F, Virelizier JL, Parmentier M, Arenzana-Seisdedos F (April 1998). "Genomic organization and promoter characterization of human CXCR4 gene". FEBS Letters. 426 (2): 271–8. doi:10.1016/S0014-5793(98)00359-7. PMID 9599023. S2CID 36571818.
  7. ^ "Gene group: C-X-C motif chemokine receptors (CXCR)". HUGO Gene Nomenclature Committee.