CXCR1 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | IL8RA | ||||||
NCBI gene | 3577 | ||||||
OMIM | 146929 | ||||||
RefSeq | NM_000634 | ||||||
UniProt | P25024 | ||||||
Other data | |||||||
Locus | Chr. 2 q35 | ||||||
|
CXCR2 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | IL8RB | ||||||
NCBI gene | 3579 | ||||||
OMIM | 146928 | ||||||
RefSeq | NM_001557 | ||||||
UniProt | P25025 | ||||||
Other data | |||||||
Locus | Chr. 2 q35 | ||||||
|
CXCR3 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | CXCR3 | ||||||
NCBI gene | 2833 | ||||||
OMIM | 300574 | ||||||
RefSeq | NM_001504 | ||||||
UniProt | P49682 | ||||||
Other data | |||||||
Locus | Chr. X q13 | ||||||
|
CXCR4 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | CXCR4 | ||||||
NCBI gene | 7852 | ||||||
OMIM | 162643 | ||||||
RefSeq | NM_001008540 | ||||||
UniProt | P61073 | ||||||
Other data | |||||||
Locus | Chr. 2 q21 | ||||||
|
CXCR5 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | BLR1 | ||||||
NCBI gene | 643 | ||||||
OMIM | 601613 | ||||||
RefSeq | NM_001716 | ||||||
UniProt | P32302 | ||||||
Other data | |||||||
Locus | Chr. 11 q23 | ||||||
|
CXCR6 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | CXCR6 | ||||||
NCBI gene | 10663 | ||||||
OMIM | 605163 | ||||||
RefSeq | NM_006564 | ||||||
UniProt | O00574 | ||||||
Other data | |||||||
Locus | Chr. 3 p21 | ||||||
|
CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins, since they span the cell membrane seven times. There are currently six known CXC chemokine receptors in mammals, named CXCR1 through CXCR6.[1][2]