CYP17A1 inhibitor

CYP17A1 inhibitor
Drug class
Abiraterone acetate, a steroidal CYP17A1 inhibitor that is used in the treatment of prostate cancer.
Class identifiers
SynonymsAndrogen synthesis inhibitors
UseProstate cancer, precocious puberty, breast cancer, others
ATC codeL02BX
Biological targetCYP17A1
Chemical classSteroidal; Nonsteroidal
Legal status
In Wikidata

A CYP17A1 inhibitor is a type of drug that inhibits the enzyme CYP17A1.[1] CYP17A1 inhibitors work by blocking specific enzyme functions, impacting androgen biosynthesis.

  1. ^ Malikova J, Brixius-Anderko S, Udhane SS, Parween S, Dick B, Bernhardt R, et al. (November 2017). "CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2". The Journal of Steroid Biochemistry and Molecular Biology. 174: 192–200. doi:10.1016/j.jsbmb.2017.09.007. PMID 28893623. S2CID 6270824.