Calcifying odontogenic cyst

Not to be confused with Odontogenic cyst or Glandular odontogenic cyst.
Calcifying odontogenic cyst
Other namesGorlin cyst, calcifying cystic odontogenic tumor[1]
This condition usually affects the jaw area
SpecialtyDentistry

Calcifying odontogenic cyst (COC) is a rare developmental lesion that comes from odontogenic epithelium.[2] It is also known as a calcifying cystic odontogenic tumor, which is a proliferation of odontogenic epithelium and scattered nest of ghost cells and calcifications that may form the lining of a cyst, or present as a solid mass.[3]

It can appear in any location in the oral cavity, but more commonly affects the anterior (front) mandible and maxilla. It is most common in individuals in their 20s to 30s, but can be seen at almost any age, regardless of gender. On dental radiographs, the calcifying odontogenic cyst appears as a unilocular (one circle) radiolucency (dark area). In one-third of cases, an impacted tooth is involved. Histologically, cells that are described as "ghost cells", enlarged eosinophilic epithelial cells without nuclei, are present within the epithelial lining and may undergo calcification.

  1. ^ Kler, Shikha; Palaskar, Sangeeta; Shetty, and, Vishwa Parkash; Bhushan, Anju (2009), "Intraosseous calcifying cystic odontogenic tumor", J Oral Maxillofac Pathol, 13 (1): 27–29, doi:10.4103/0973-029X.48753, PMC 3162852, PMID 21886994.
  2. ^ Zornosa, Ximena; Müller, Susan (2010-07-24). "Calcifying Cystic Odontogenic Tumor". Head and Neck Pathology. 4 (4): 292–294. doi:10.1007/s12105-010-0197-z. ISSN 1936-055X. PMC 2996493. PMID 20658217.
  3. ^ Gamoh, Shoko; Akiyama, Hironori; Furukawa, Chisato; Matsushima, Yuki; Iseki, Tomio; Wato, Masahiro; Tanaka, Akio; Morita, Shosuke; Shimizutani, Kimishige (2017-11-01). "Calcifying cystic odontogenic tumor accompanied by a dentigerous cyst: A case report". Oncology Letters. 14 (5): 5785–5790. doi:10.3892/ol.2017.6993. ISSN 1792-1074. PMC 5661555. PMID 29113208.