Calponin

Calponin Homology Domain
CH domain from H.Sapiends Calponin 1. PDB 1wyp
Identifiers
Symbol	CH
Pfam	PF00307
Pfam clan	CL0188
InterPro	IPR001715
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

calponin 1, basic, smooth muscle
Solution structure of the CH domain of human Calponin 1. Rainbow colored cartoon (N-terminus = blue, C-terminus = red).[1]
Identifiers
Symbol	CNN1
NCBI gene	1264
HGNC	2155
OMIM	600806
PDB	1WYP
RefSeq	NM_001299
UniProt	P51911
Other data
Locus	Chr. 19 p13.2-13.1
Search for Structures Swiss-model Domains InterPro

Calponin is a calcium binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein kinase, which is dependent upon calcium binding to calmodulin, releases the calponin's inhibition of the smooth muscle ATPase.