Canarypox

Canarypox virus
Virus classification Edit this classification
(unranked): Virus
Realm: Varidnaviria
Kingdom: Bamfordvirae
Phylum: Nucleocytoviricota
Class: Pokkesviricetes
Order: Chitovirales
Family: Poxviridae
Genus: Avipoxvirus
Species:
Canarypox virus
Canary bird (Serinus canaria) with its typical yellow colouration.

Canarypox virus (CNPV) is an Avipoxvirus and etiologic agent of canarypox, a disease of wild and captive birds that can cause significant losses. Canarypox can enter human cells, but it cannot survive and multiply in human cells.[1] There is a live viral vaccine available which may have beneficial properties against human cancer when used as a mammalian expression vector.[2] (ATCvet code: QI01KD01 (WHO)). Furthermore, the Poximune C vaccine does offer direct protection against CNPV in susceptible birds.[3]

Generally CNPV is considered a disease of songbirds, such as canaries, magpies and nightingales, and is associated with higher mortality rates when compared to other avian pox viruses.[4] In some instances, mortality approaches 100%.[4] Avian pox viruses also cause significant economic losses in domestic poultry and remain a problem in the conservation of endemic bird species inhabiting islands.[5]

The general symptoms of CNPV are similar to those of other species of avian pox viruses and are characterised by pustules and diphtheria or pneumonia-like symptoms.[1]

  1. ^ a b "Canary Pox Virus". BeautyOfBirds, formerly AvianWeb. Retrieved 22 March 2012.
  2. ^ Bos, R; van Duikeren, S.; van Hall, T.; Lauwen, M.M.; Parrington, M.; Berinstein, N.L.; McNeil, B.; Melief, C.J.; Verbeek, J.S.; van der Burg, S.H.; Offringa, R. (Nov 1, 2007). "Characterization of antigen-specific immune responses induced by canarypox virus vaccines". Journal of Immunology. 179 (9): 6115–22. doi:10.4049/jimmunol.179.9.6115. PMID 17947686.
  3. ^ "Poximune C". Drugs.com. Retrieved 22 March 2012.
  4. ^ a b "VaxQuery Database". Canarypox virus. VaxQuery. Archived from the original on 14 January 2020. Retrieved 22 March 2012.
  5. ^ Thiel, T; Whiteman, NK; Tirapé, A; Baquero, MI; Cedeño, V; Walsh, T; Uzcátegui, GJ; Parker, PG (April 2005). "Characterization of canarypox-like viruses infecting endemic birds in the Galápagos Islands". Journal of Wildlife Diseases. 41 (2): 342–53. doi:10.7589/0090-3558-41.2.342. PMID 16107669. S2CID 8194562.