Cancer dormancy

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Dormancy is a stage in cancer progression where the cells cease dividing but survive in a quiescent state while waiting for appropriate environmental conditions to begin proliferation again.^[1] Quiescence is the state where cells are not dividing but at arrest in the cell cycle in G0-G1.^[1] Dormant cancer cells are thought to be present in early tumor progression, in micrometastases, or left behind in minimal residual disease (MRD) after what was thought to be a successful treatment of the primary tumor.^[2]