Candoxatril

Candoxatril
Names
	Preferred IUPAC name (1R,4s)-4-(1-{(2S)-3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl}cyclopentan-1-amido)cyclohexane-1-carboxylic acid
Identifiers
CAS Number	123122-55-4 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL35084;
ChemSpider	16736409;
DrugBank	DB00616;
MeSH	candoxatril
PubChem CID	122116; 5362417;
UNII	ACP75508EE ;
CompTox Dashboard (EPA)	DTXSID6047286 ;
	InChI InChI=1S/C29H41NO7/c1-35-15-16-36-19-23(27(33)37-25-12-9-20-5-4-6-22(20)17-25)18-29(13-2-3-14-29)28(34)30-24-10-7-21(8-11-24)26(31)32/h9,12,17,21,23-24H,2-8,10-11,13-16,18-19H2,1H3,(H,30,34)(H,31,32);
	SMILES O=C(NC1CCC(C(=O)O)CC1)C4(CC(C(=O)Oc2cc3c(cc2)CCC3)COCCOC)CCCC4;
Properties
Chemical formula	C29H41NO7
Molar mass	515.647 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Candoxatril is the orally active prodrug^[1] of candoxatrilat (UK-73967).

^ Maw GN, Stobie A, Planken S, Pryde DC, Sanderson V, Platts MY, Corless M, Stacey P, Wayman C, Van Der Graaf P, Kohl C, Coggon S, Beaumont K (January 2006). "The discovery of small molecule inhibitors of neutral endopeptidase. Structure-activity studies on functionalized glutaramides". Chemical Biology & Drug Design. 67 (1): 74–77. doi:10.1111/j.1747-0285.2005.00320.x. PMID 16492151.