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Cannabis on American Indian reservations was historically regulated under United States federal law. However, the August 2013 issuance of the Cole Memorandum opened discussion on tribal sovereignty pertaining to cannabis legalization.[1] A clarifying memo in December 2014 stated that the federal government's non-interference policies that applied to the 50 states, would also apply to the 326 recognized American Indian reservations.[2][1][3] Reservations are therefore able to independently regulate cannabis possession and sale irrespective of laws in any bordering US states.[3]