Capgras delusion

Capgras delusion
Other namesCapgras syndrome
Pronunciation
SpecialtyPsychiatry
SymptomsDelusion that familiar people or pets have been replaced by identical imposters; aggression with the person suspected as an imposter
ComplicationsViolence, homicide
CausesUncertain; exacerbated by head injury
Risk factorsNeuroanatomical damage, schizophrenia
PreventionUnknown
TreatmentNo cure; therapy generally used
MedicationAntipsychotics

Capgras delusion or Capgras syndrome is a psychiatric disorder in which a person holds a delusion that a friend, spouse, parent, another close family member, or pet has been replaced by an identical impostor.[a] It is named after Joseph Capgras (1873–1950), the French psychiatrist who first described the disorder.

The Capgras delusion is classified as a delusional misidentification syndrome, a class of delusional beliefs that involves the misidentification of people, places, or objects.[2] It can occur in acute, transient, or chronic forms. Cases in which patients hold the belief that time has been "warped" or "substituted" have also been reported.[3]

The delusion most commonly occurs in individuals diagnosed with a psychotic disorder, usually schizophrenia,[4] but has also been seen in brain injury,[5] dementia with Lewy bodies,[6] and other forms of dementia.[7] It presents often in individuals with a neurodegenerative disease, particularly at an older age;[8] it has also been reported as occurring in association with diabetes, hypothyroidism, and migraine attacks.[9] In one isolated case, the Capgras delusion was temporarily induced in a healthy subject by administration of ketamine.[10] It occurs more frequently in females, with a female to male ratio of approximately 3∶2.[11]

  1. ^ "Capgras' delusion patient" – via www.youtube.com.
  2. ^ Ellis, Hadyn D.; Lewis, Michael B. (2001-04-01). "Capgras delusion: a window on face recognition". Trends in Cognitive Sciences. 5 (4): 149–156. doi:10.1016/S1364-6613(00)01620-X. PMID 11287268. S2CID 14058637.
  3. ^ Aziz, V.M.; Warner, N.J. (2005). "Capgras' Syndrome of Time". Psychopathology. 38 (1): 49–52. doi:10.1159/000083970. PMID 15722649. S2CID 21363443.
  4. ^ Bhandari, Sadgun (2012-01-01), Wright, Pádraig; Stern, Julian; Phelan, Michael (eds.), "23 - Unusual psychiatric syndromes", Core Psychiatry (Third Edition), Oxford: W.B. Saunders, pp. 349–357, ISBN 978-0-7020-3397-1, retrieved 2024-02-01
  5. ^ Ramachandran, V. S. (1998). "Consciousness and body image: Lessons from phantom limbs, Capgras syndrome and pain asymbolia". Philosophical Transactions of the Royal Society B: Biological Sciences. 353 (1377): 1851–1859. doi:10.1098/rstb.1998.0337. PMC 1692421. PMID 9854257.
  6. ^ Gomperts SN (April 2016). "Lewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease Dementia". Continuum (Minneap Minn) (Review). 22 (2 Dementia): 435–63. doi:10.1212/CON.0000000000000309. PMC 5390937. PMID 27042903.
  7. ^ Förstl, H; Almeida, O.P.; Owen, A.M.; Burns, A.; Howard, R. (November 1991). "Psychiatric, neurological and medical aspects of misidentification syndromes: a review of 260 cases". Psychol Med. 21 (4): 905–10. doi:10.1017/S0033291700029895. PMID 1780403. S2CID 24026245.
  8. ^ Josephs, K. A. (December 2007). "Capgras Syndrome and Its Relationship to Neurodegenerative Disease". Archives of Neurology. 64 (12): 1762–1766. doi:10.1001/archneur.64.12.1762. PMID 18071040.
  9. ^ Bhatia, M.S (1990). "Capgras syndrome in a patient with migraine". British Journal of Psychiatry. 157 (6): 917–918. doi:10.1192/bjp.157.6.917. PMID 2289104. S2CID 36280494.
  10. ^ Corlett, P.R.; D'Souza, D.C.; Krystal, J.H. (July 2010). "Capgras Syndrome Induced by Ketamine in a Healthy Subject". Biological Psychiatry. 68 (1): e1–e2. doi:10.1016/j.biopsych.2010.02.015. PMC 3721067. PMID 20385373.
  11. ^ Giannini AJ, Black HR (1978-01-01). The Psychiatric, Psychogenic and Somatopsychic Disorders Handbook. Garden City, NY: Medical Examination. pp. 97–8. ISBN 978-0-87488-596-5.


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