Carnitine-acylcarnitine translocase

SLC25A20
Identifiers
Aliases	SLC25A20, CAC, CACT, Carnitine-acylcarnitine translocase, solute carrier family 25 member 20
External IDs	OMIM: 613698; MGI: 1928738; HomoloGene: 331; GeneCards: SLC25A20; OMA:SLC25A20 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.31 Start 48,856,926 bp[1] End 48,898,904 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F2 Start 108,539,287 bp[2] End 108,561,840 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver mucosa of transverse colon apex of heart mucosa of ileum granulocyte left ventricle gastrocnemius muscle duodenum jejunal mucosa muscle of thigh Top expressed in brown adipose tissue tunica adventitia of aorta interventricular septum intercostal muscle soleus muscle myocardium of ventricle thoracic diaphragm left lobe of liver right ventricle extraocular muscle More reference expression data BioGPS n/a
Gene ontology Molecular function acyl carnitine transmembrane transporter activity carnitine:acyl carnitine antiporter activity carnitine transmembrane transporter activity transmembrane transporter activity Cellular component membrane mitochondrion cytosol mitochondrial inner membrane integral component of membrane Biological process carnitine shuttle acyl carnitine transmembrane transport mitochondrial transport carnitine transport carnitine transmembrane transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 788 57279 Ensembl ENSG00000178537 ENSMUSG00000032602 UniProt O43772 Q9Z2Z6 RefSeq (mRNA) NM_000387 NM_020520 RefSeq (protein) NP_000378 NP_065266 Location (UCSC) Chr 3: 48.86 – 48.9 Mb Chr 9: 108.54 – 108.56 Mb PubMed search [3] [4]
Wikidata
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Carnitine-acylcarnitine translocase (CACT) is responsible for passive transport of carnitine and carnitine-fatty acid complexes and across the inner mitochondrial membrane as part of the carnitine shuttle system.