Carprofen

Carprofen
	Carprofen molecule
Clinical data
Trade names	Rimadyl
AHFS/Drugs.com	FDA Professional Drug Information
License data	US DailyMed: Carprofen;
Routes of; administration	By mouth, injection
ATCvet code	QM01AE91 (WHO) ;
Legal status
Legal status	US: ℞-only Veterinary use only; EU: Rx-only;
Pharmacokinetic data
Protein binding	High (99%)
Elimination half-life	Approximately 8 h (range 4.5–9.8 h) in dogs
Identifiers
	IUPAC name (RS)-2-(6-Chloro-9H-carbazol-2-yl)propanoic acid;
CAS Number	53716-49-7 ;
PubChem CID	2581;
IUPHAR/BPS	7141;
DrugBank	DB00821 ;
ChemSpider	2483 ;
UNII	FFL0D546HO;
KEGG	D03410 ;
ChEBI	CHEBI:364453 ;
ChEMBL	ChEMBL1316 ;
CompTox Dashboard (EPA)	DTXSID1045871 ;
ECHA InfoCard	100.053.357
Chemical and physical data
Formula	C15H12ClNO2
Molar mass	273.72 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES CC(C1=CC=C2C(NC3=CC=C(C=C32)Cl)=C1)C(O)=O;
	InChI InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19) ; Key:PUXBGTOOZJQSKH-UHFFFAOYSA-N ;
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Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the carbazole and propionic acid class that was previously for use in humans and animals but is now only available to veterinarians for prescribing as a supportive treatment for various conditions in animals.^[1] Carprofen reduces inflammation by inhibition of COX-1 and COX-2; its specificity for COX-2 varies from species to species.^[1] Marketed under many brand names worldwide,^[3] carprofen is used as a treatment for inflammation and pain, including joint pain and postoperative pain.^[1]

^ ^a ^b ^c ^d "Rimadyl (carprofen) prescribing information leaflet" (PDF). www2.ZoetisUS.com. Zoetis Inc. Retrieved 5 February 2022.
^ Cite error: The named reference Carprofen Orion EPAR was invoked but never defined (see the help page).
^ "International brand names for Carprofen". www.Drugs.com. Drugs.com. Retrieved 4 October 2017.