Cefaclor

Cefaclor
Clinical data
Trade namesBiocef, Ceclor, Medacef, Distaclor, Keflor, Raniclor
AHFS/Drugs.comMonograph
MedlinePlusa682729
Pregnancy
category
  • AU: B1
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityWell absorbed, independent of food intake
Metabolism15% to 40%
Elimination half-life0.6 to 0.9 hours
ExcretionRenal
Identifiers
  • (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}- 3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene- 2-carboxylic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.053.536 Edit this at Wikidata
Chemical and physical data
FormulaC15H14ClN3O4S
Molar mass367.80 g·mol−1
3D model (JSmol)
  • O=C2N1/C(=C(/Cl)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccccc3)N)C(=O)O.O
  • InChI=1S/C15H14ClN3O4S.H2O/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7;/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23);1H2/t9-,10-,14-;/m1./s1 checkY
  • Key:WKJGTOYAEQDNIA-IOOZKYRYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Cefaclor, sold under the trade name Ceclor among others, is a second-generation cephalosporin antibiotic used to treat certain bacterial infections such as pneumonia and infections of the ear, lung, skin, throat, and urinary tract. It is also available from other manufacturers as a generic.[1]

It was patented in 1973 and approved for medical use in 1979.[2]

  1. ^ "Drugs@FDA: FDA-Approved Drugs".
  2. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 493. ISBN 9783527607495.