Cellular adoptive immunotherapy

Immune cell lineage

Cellular adoptive immunotherapy is a type of immunotherapy. Immune cells such as T-cells are usually isolated from patients for expansion or engineering purposes and reinfused back into patients to fight diseases using their own immune system. A major application of cellular adoptive therapy is cancer treatment, as the immune system plays a vital role in the development and growth of cancer.[1] The primary types of cellular adoptive immunotherapies are T cell therapies. Other therapies include CAR-T therapy, CAR-NK therapy, macrophage-based immunotherapy and dendritic cell therapy.

  1. ^ Rohaan, Maartje W.; Wilgenhof, Sofie; Haanen, John B. A. G. (2018-11-23). "Adoptive cellular therapies: the current landscape". Virchows Archiv. 474 (4): 449–461. doi:10.1007/s00428-018-2484-0. ISSN 1432-2307. PMC 6447513. PMID 30470934.