Centromedian nucleus

Centromedian nucleus
Centromedian nucleus inside left thalamus
Details
Part ofIntralaminar thalamic nuclei
Identifiers
Latinnucleus centromedianus thalami
Acronym(s)CM or Cm-Pf
NeuroNames323
NeuroLex IDbirnlex_805
TA98A14.1.08.618
FMA62165
Anatomical terms of neuroanatomy

In the anatomy of the brain, the centromedian nucleus, also known as the centrum medianum, (CM or Cm-Pf) is a nucleus in the posterior group of the intralaminar thalamic nuclei (ITN) in the thalamus. (This must not be confused with the central medial nucleus, which is in the anterior group of the ITN.) There are two centromedian nuclei arranged bilaterally.

In humans, each centromedian nucleus contains about 2200 neurons per cubic millimetre and has a volume of about 310 cubic millimetres with 664,000 neurons in total.[1] It measures less than 10 millimetres in every dimension.[2] It belongs to the caudal intralaminar group of thalamic nuclei and is situated within the medial thalamus. It is bordered superiorly by the mediodorsal nucleus, medially by the parafascicular nucleus, and posteriorly by the pulvinar.[2][3]

  1. ^ Henderson J, Carpenter K, Cartwright H, Halliday G (2000). "Loss of thalamic intralaminar nuclei in progressive supranuclear palsy and Parkinson's disease: clinical and therapeutic implications". Brain. 123 (7): 1410–1421. doi:10.1093/brain/123.7.1410. PMID 10869053. Archived from the original on 2004-12-25. Retrieved 2004-09-24.
  2. ^ a b Remore, Luigi G.; Rifi, Ziad; Bari, Ausaf A. (2023). "Structural connections of the centromedian nucleus of thalamus and their relevance for neuromodulation in generalized drug-resistant epilepsy: insight from a tractography study". Therapeutic Advances in Neurological Disorders. 16: 1–17. doi:10.1177/17562864231202064. PMC 10563482. PMID 37822361.
  3. ^ Ilyas, Adeel; Pizarro, Diana; Romeo, Andrew K.; Riley, Kristen O; Pati, Sandipan (2019). "The centromedian nucleus: Anatomy, physiology, and clinical implications". Journal of Clinical Neuroscience. 63: 1–7. doi:10.1016/j.jocn.2019.01.050. PMID 30827880. Retrieved 22 September 2024.