Cetuximab

Cetuximab
Monoclonal antibody
TypeWhole antibody
SourceChimeric (mouse/human)
TargetEGF receptor
Clinical data
Trade namesErbitux
AHFS/Drugs.comMonograph
License data
Pregnancy
category
  • AU: D
Routes of
administration
Intravenous
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-life114 hrs
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC6484H10042N1732O2023S36
Molar mass145781.92 g·mol−1
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Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer.[2] Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion.[2]

Cetuximab was approved for medical use in the United States in 2004.[4]

  1. ^ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
  2. ^ a b c "Erbitux- cetuximab solution". DailyMed. 27 September 2021. Archived from the original on 20 October 2021. Retrieved 2 June 2022.
  3. ^ "Erbitux EPAR". European Medicines Agency. 17 September 2018. Archived from the original on 14 May 2021. Retrieved 2 June 2022.
  4. ^ "Drug Approval Package: Erbitux BLA 125084". accessdata.fda.gov. 13 September 2004. Retrieved 17 August 2024.