Charles Erskine may refer to:
- Sir Charles Erskine, 1st Baronet of Alva (1643–1690), Scottish politician
- Charles Erskine, Earl of Mar (1650–1689), Scottish nobleman
- Charles Erskine, Lord Tinwald (1680–1763), Scottish judge, Lord Advocate, MP for Dumfriesshire 1722–41 and for Tain Burghs 1734–42
- Charles Erskine (1716–1749), his son, Scottish lawyer, MP for Ayr Burghs
- Charles Erskine (cardinal) (1739–1811), Italian-Scottish papal diplomat and cardinal
This disambiguation page lists articles about people with the same name.
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