Charles Ryan may refer to:
- Sir Charles Lister Ryan (1831–1920), English civil servant
- Sir Charles Ryan (surgeon) (1853–1926), Australian surgeon and army officer
- Charles Ryan (mayor) (1927–2021), American politician and mayor of Springfield, Massachusetts
- Charles Ryan (game designer), American game designer of role-playing games
- Charles Ryan (footballer), English footballer
This disambiguation page lists articles about people with the same name.
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