Charles Scott Sherrington

Sir Charles Scott Sherrington
43rd President of the Royal Society
In office
1920–1925
Preceded byJ. J. Thomson
Succeeded byErnest Rutherford
Personal details
Born(1857-11-27)27 November 1857
Islington, Middlesex, England, United Kingdom of Great Britain and Ireland
Died4 March 1952(1952-03-04) (aged 94)
Eastbourne, Sussex, England, United Kingdom
CitizenshipBritish
Alma mater
Awards
Scientific career
Fields
Institutions
Academic advisors
Doctoral students

Sir Charles Scott Sherrington OM GBE FRS FRCP FRCS[1][3] (27 November 1857 – 4 March 1952) was a British neurophysiologist. His experimental research established many aspects of contemporary neuroscience, including the concept of the spinal reflex as a system involving connected neurons (the "neuron doctrine"), and the ways in which signal transmission between neurons can be potentiated or depotentiated. Sherrington himself coined the word "synapse" to define the connection between two neurons. His book The Integrative Action of the Nervous System (1906)[4] is a synthesis of this work, in recognition of which he was awarded the Nobel Prize in Physiology or Medicine in 1932 (along with Edgar Adrian).[5][6][7][8]

In addition to his work in physiology, Sherrington did research in histology, bacteriology, and pathology. He was president of the Royal Society in the early 1920s.

  1. ^ a b Cite error: The named reference onfrsV8 was invoked but never defined (see the help page).
  2. ^ Todman, Donald (2008). "Howard Florey and research on the cerebral circulation". Journal of Clinical Neuroscience. 15 (6): 613–616. doi:10.1016/j.jocn.2007.04.017. PMID 18280740. S2CID 40353145. His mentor was the neurophysiologist and Nobel Laureate, Sir Charles Sherrington who directed him in neuroscience research. Florey's initial studies on the cerebral circulation represent an original contribution to medical knowledge and highlight his remarkable scientific method. The mentorship and close personal relationship with Sherrington was a crucial factor in Florey's early research career.
  3. ^ Sherrington, C. E. (1975). "Charles Scott Sherrington (1857–1952)". Notes and Records of the Royal Society of London. 30 (1): 45–63. doi:10.1098/rsnr.1975.0005. PMID 11615580. S2CID 42127498.
  4. ^ Sherrington, Charles Scott (1906). The integrative action of the nervous system (1st ed.). Oxford University Press: H. Milford. pp. xvi, 411 p., [19] leaves of plates.
  5. ^ ""Sir Charles Sherrington – Nobel Lecture: Inhibition as a Coordinative Factor"". Retrieved 31 July 2012.
  6. ^ "Sir Charles Scott Sherrington". Encyclopædia Britannica, Inc. Retrieved 31 July 2012.
  7. ^ Pearce, J. M. (2004). "Sir Charles Scott Sherrington (1857–1952) and the synapse". Journal of Neurology, Neurosurgery, and Psychiatry. 75 (4): 544. doi:10.1136/jnnp.2003.017921. PMC 1739021. PMID 15026492.
  8. ^ Penfield, W. (1962). "Sir Charles Sherrington, O.M., F.R.S. (1857–1952): An Appreciation". Notes and Records of the Royal Society. 17 (2): 163–168. doi:10.1098/rsnr.1962.0015. S2CID 145536063.