| Chicken anemia virus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Family: | Anelloviridae |
| Genus: | Gyrovirus |
| Species: | Chicken anemia virus
|
| Synonyms | |
|
Chicken anaemia virus | |
Chicken anemia virus, or CAV, is currently a member of the Anelloviridae family which is found worldwide.[1] The virus only affects chickens.[2] CAV is a non-enveloped icosahedral single stranded DNA virus,[3] which causes bone marrow atrophy, anemia, and severe immunosuppression. Clinical signs of CAV infection are predominantly found in young chicks due to vertical transmission from the breeder hens whose maternal antibodies have not yet formed following exposure. Clinical disease is rare today because of the widespread practice of vaccinating breeders, but the subclinical form of the disease—which normally affects birds more than two weeks of age following horizontal transmission of the virus via the fecal–oral route—is ubiquitous. The virus is very resistant in the environment, making elimination very difficult.
The disease and virus have many names including chicken anemia, blue wing disease, anemia dermatitis syndrome, chicken/avian infectious anemia, hemorrhagic aplastic anemia syndrome, infectious chicken anemia, chicken infectious anemia virus, and chicken anemia agent.[citation needed] When this virus was first discovered in 1979, it was named chicken anemia agent.[1]
- ^ a b Schat, KA (2009). "Chicken Anemia Virus". TT Viruses. Current Topics in Microbiology and Immunology. Vol. 331. pp. 151–83. doi:10.1007/978-3-540-70972-5_10. ISBN 978-3-540-70971-8. PMID 19230563.
- ^ Cite error: The named reference
Markey 2013was invoked but never defined (see the help page). - ^ Fang, L; Li, Y; Wang, Y; Fu, J; Cui, S; Li, X; Chang, S; Zhao, P (2017). "Genetic Analysis of Two Chicken Infectious Anemia Virus Variants-Related Gyrovirus in Stray Mice and Dogs: The First Report in China, 2015". BioMed Research International. 2017: 6707868. doi:10.1155/2017/6707868. PMC 5343220. PMID 28326326.