Children's Medical Research Institute

Children's Medical Research Institute
Established	1958
Research type	Medical research
Field of research	Genetic research;; Cancer;; Epilepsy;; Birth defects
Director	Professor Roger Reddel AO FAA
Address	214 Hawkesbury Road, Westmead NSW 2145
Location	Sydney, New South Wales, Australia; 33°48′05″S 150°59′32″E / 33.80139°S 150.99222°E
Campus	Westmead
Affiliations	University of Sydney; The Children's Hospital at Westmead;
Website	cmri.org.au

Children's Medical Research Institute (CMRI) is an Australian medical research institute located in Westmead that conducts research into children's genetic diseases. As of 2019^[update], current research is focused on cancer, birth defects, neurological conditions such as epilepsy, and gene therapy.^[1]

Much of CMRI's cancer research focuses on telomeres (including telomerase) and the Alternative Lengthening of Telomeres (ALT) mechanism, which was discovered at CMRI in 1997.^[2]

^ "About Us". Children's Medical Research Institute.
^ Bryan, Tracy M.; Englezou, Anna; Dalla-Pozza, Luciano; Dunham, Melissa A.; Reddel, Roger R. (1997). "Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines". Nature Medicine. 3 (11): 1271–1274. doi:10.1038/nm1197-1271. ISSN 1078-8956. PMID 9359704.

[1] "About Us". Children's Medical Research Institute.

[2] Bryan, Tracy M.; Englezou, Anna; Dalla-Pozza, Luciano; Dunham, Melissa A.; Reddel, Roger R. (1997). "Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines". Nature Medicine. 3 (11): 1271–1274. doi:10.1038/nm1197-1271. ISSN 1078-8956. PMID 9359704.

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