Chlormezanone

"Trancopal" redirects here. For Trancopal Dolo, see Flupirtine.
Chlormezanone
Skeletal formula of chlormezanone
Space-filling model of the chlormezanone molecule
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Elimination half-life40.5 hours
Identifiers
  • 2-(4-chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.190 Edit this at Wikidata
Chemical and physical data
FormulaC11H12ClNO3S
Molar mass273.73 g·mol−1
3D model (JSmol)
  • O=S1(CCC(N(C)C1C2=CC=C(C=C2)Cl)=O)=O
  • InChI=1S/C11H12ClNO3S/c1-13-10(14)6-7-17(15,16)11(13)8-2-4-9(12)5-3-8/h2-5,11H,6-7H2,1H3 checkY
  • Key:WEQAYVWKMWHEJO-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Chlormezanone (marketed under the brandname Trancopal or Fenaprim) is a drug used as an anxiolytic and a muscle relaxant.[1]

Its use was discontinued in many countries in 1996 due to rare but serious cases of toxic epidermal necrolysis.[2]

  1. ^ Turner P, Volan G, Wiseman H (1997). Drugs Handbook. UK: Palgrave Macmillan. p. 20. ISBN 978-1-349-13937-8.
  2. ^ Lerch M, Mainetti C, Terziroli Beretta-Piccoli B, Harr T (February 2018). "Current Perspectives on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis". Clinical Reviews in Allergy & Immunology. 54 (1): 147–176. doi:10.1007/s12016-017-8654-z. PMID 29188475. S2CID 46796285.