Cholecystokinin

CCK
Identifiers
AliasesCCK, cholecystokinin
External IDsOMIM: 118440; MGI: 88297; HomoloGene: 583; GeneCards: CCK; OMA:CCK - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000729
NM_001174138

NM_031161
NM_001284508

RefSeq (protein)

NP_000720
NP_001167609

NP_001271437
NP_112438

Location (UCSC)Chr 3: 42.26 – 42.27 MbChr 9: 121.32 – 121.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cholecystokinin (CCK or CCK-PZ; from Greek chole, "bile"; cysto, "sac"; kinin, "move"; hence, move the bile-sac (gallbladder)) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, formerly called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum, the first segment of the small intestine. Its presence causes the release of digestive enzymes and bile from the pancreas and gallbladder, respectively..[5][6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187094Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032532Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Johnson LR (2013). Gastrointestinal Physiology (Eighth ed.). Philadelphia: Elsevier/Mosby. ISBN 978-0-323-10085-4.
  6. ^ Bowen R (28 January 2001). "Cholecystokinin". Colorado State University. Archived from the original on 17 March 2016. Retrieved 6 November 2015.