Cholinergic crisis

Cholinergic crisis
Other namesCholinergic toxicity, cholinergic poisoning, SLUDGE syndrome

A cholinergic crisis is an over-stimulation at a neuromuscular junction due to an excess of acetylcholine (ACh),[1] as a result of the inactivity of the AChE enzyme, which normally breaks down acetylcholine.

  1. ^ Asensio JA, Trunkey DD (Apr 20, 2015). Current Therapy of Trauma and Surgical Critical Care E-Book. Elsevier Health Sciences. p. 31. ISBN 9780323079808. Retrieved 2 October 2017.