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17th-century missionary activity in Asia and the Americas grew strongly, put down roots, and developed its institutions, though it met with strong resistance in Japan in particular. At the same time Christian colonization of some areas outside Europe succeeded, driven by economic as well as religious reasons. Christian traders were heavily involved in the Atlantic slave trade, which had the effect of transporting Africans into Christian communities. A land war between Christianity and Islam continued, in the form of the campaigns of the Habsburg Empire and Ottoman Empire in the Balkans, a turning point coming at Vienna in 1683. The Tsardom of Russia, where Orthodox Christianity was the established religion, expanded eastwards into Siberia and Central Asia, regions of Islamic and shamanistic beliefs, and also southwest into Ukraine, where the Uniate Eastern Catholic Churches arose.
There was a very large volume of Christian literature published, particularly controversial and millennial but also historical and scholarly. Hagiography became more critical with the Bollandists, and ecclesiastical history became thoroughly developed and debated, with Catholic scholars such as Baronius and Jean Mabillon, and Protestants such as David Blondel laying down the lines of scholarship. Christian art of the Baroque and music derived from church forms was striking and influential on lay artists using secular expression and themes. Poetry and drama often treated Biblical and religious matter, for example John Milton's Paradise Lost.