Chromosome 1

Chromosome 1
Human chromosome 1 pair after G-banding. One is from mother, one is from father.
Chromosome 1 pair
in human male karyogram.
Features
Length (bp)248,387,328 bp
(CHM13)
No. of genes1,961 (CCDS)[1]
TypeAutosome
Centromere positionMetacentric[2]
(123.4 Mbp[3])
Complete gene lists
CCDSGene list
HGNCGene list
UniProtGene list
NCBIGene list
External map viewers
EnsemblChromosome 1
EntrezChromosome 1
NCBIChromosome 1
UCSCChromosome 1
Full DNA sequences
RefSeqNC_000001 (FASTA)
GenBankCM000663 (FASTA)

Chromosome 1 is the designation for the largest human chromosome. Humans have two copies of chromosome 1, as they do with all of the autosomes, which are the non-sex chromosomes. Chromosome 1 spans about 249 million nucleotide base pairs, which are the basic units of information for DNA.[4] It represents about 8% of the total DNA in human cells.[5]

It was the last completed chromosome, sequenced two decades after the beginning of the Human Genome Project.

  1. ^ Cite error: The named reference CCDS was invoked but never defined (see the help page).
  2. ^ Tom Strachan; Andrew Read (2 April 2010). Human Molecular Genetics. Garland Science. p. 45. ISBN 978-1-136-84407-2.
  3. ^ Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
  4. ^ http://vega.sanger.ac.uk/Homo_sapiens/mapview?chr=1 Chromosome size and number of genes derived from this database, retrieved 2012-03-11.
  5. ^ Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, et al. (May 2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.