Chronic prostatitis/chronic pelvic pain syndrome

This article is about one kind of chronic pelvic pain in males. For females, see pelvic pain.

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)
Other nameschronic nonbacterial prostatitis, prostatodynia, painful prostate
SpecialtyUrology
CausesUnknown[1]
Differential diagnosisBacterial prostatitis, benign prostatic hypertrophy, overactive bladder, cancer[2]
Frequency~4%[3]

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), previously known as chronic nonbacterial prostatitis, is long-term pelvic pain and lower urinary tract symptoms (LUTS) without evidence of a bacterial infection.[3] It affects about 2–6% of men.[3] Together with IC/BPS, it makes up urologic chronic pelvic pain syndrome (UCPPS).[4]

The cause is unknown.[1] Diagnosis involves ruling out other potential causes of the symptoms such as bacterial prostatitis, benign prostatic hypertrophy, overactive bladder, and cancer.[2][5]

Recommended treatments include multimodal therapy, physiotherapy, and a trial of alpha blocker medication or antibiotics in certain newly diagnosed cases.[6] Some evidence supports some non medication based treatments.[7]

  1. ^ a b Franco JV, Turk T, Jung JH, Xiao YT, Iakhno S, Garrote V, et al. (12 May 2018). "Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome". Cochrane Database of Systematic Reviews. 2018 (5): CD012551. doi:10.1002/14651858.CD012551.pub3. PMC 6494451. PMID 29757454.
  2. ^ a b Doiron RC, Nickel JC (June 2018). "Evaluation of the male with chronic prostatitis/chronic pelvic pain syndrome". Canadian Urological Association Journal. 12 (6 Suppl 3): S152–S154. doi:10.5489/cuaj.5322. PMC 6040610. PMID 29875039.
  3. ^ a b c Doiron RC, Nickel JC (June 2018). "Management of chronic prostatitis/chronic pelvic pain syndrome". Canadian Urological Association Journal. 12 (6 Suppl 3): S161–S163. doi:10.5489/cuaj.5325. PMC 6040620. PMID 29875042.
  4. ^ Adamian L, Urits I, Orhurhu V, Hoyt D, Driessen R, Freeman JA, et al. (May 2020). "A Comprehensive Review of the Diagnosis, Treatment, and Management of Urologic Chronic Pelvic Pain Syndrome". Curr Pain Headache Rep. 24 (6): 27. doi:10.1007/s11916-020-00857-9. PMID 32378039. S2CID 218513050.
  5. ^ Holt JD, Garrett WA, McCurry TK, Teichman JM (2016). "Common Questions About Chronic Prostatitis". Am Fam Physician. 93 (4): 290–296. PMID 26926816.
  6. ^ Ferri FF (2018). Ferri's Clinical Advisor 2019 E-Book: 5 Books in 1. Elsevier Health Sciences. p. 1149. ISBN 9780323550765. Archived from the original on 2023-06-30. Retrieved 2020-09-19.
  7. ^ Franco JV, Turk T, Jung JH, Xiao YT, Iakhno S, Garrote V, et al. (12 May 2018). "Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome". The Cochrane Database of Systematic Reviews. 2018 (5): CD012551. doi:10.1002/14651858.CD012551.pub3. ISSN 1469-493X. PMC 6494451. PMID 29757454.