Ciliogenesis

Ciliogenesis
Details
Identifiers
LatinCiliogenesis
THH1.00.01.1.01033
Anatomical terminology
EVOS Imaging depicting a single celled organism with distinctive cilia

Ciliogenesis is defined as the building of the cell's antenna (primary cilia) or extracellular fluid mediation mechanism (motile cilium).[1] It includes the assembly and disassembly of the cilia during the cell cycle. Cilia are important appendages of cells and are involved in numerous activities such as cell signaling, processing developmental signals, and directing the flow of fluids such as mucus over and around cells. Due to the importance of these cell processes, defects in ciliogenesis can lead to numerous human diseases related to non-functioning cilia known as ciliopathies.[1]

  1. ^ a b Ishikawa H, Marshall WF (April 2011). "Ciliogenesis: building the cell's antenna". Nature Reviews. Molecular Cell Biology. 12 (4): 222–234. doi:10.1038/nrm3085. PMID 21427764. S2CID 33628277.