Cingulum (brain)

Cingulum
Medial surface of right cerebral hemisphere. Some of major association tracts are depicted. Cingulum is at center, in red.
Tractography of cingulum. Animation.
Details
Identifiers
Latincingulum
NeuroNames1445
TA98A14.1.09.555
A05.1.03.044
TA25597
FMA260761
Anatomical terms of neuroanatomy

In neuroanatomy, the cingulum or cingulum bundle is an association tract, a nerve tract that projects from the cingulate gyrus to the entorhinal cortex in the brain, allowing for communication between components of the limbic system.[1] It forms the white matter core of the cingulate gyrus, following it from the subcallosal gyrus of the frontal lobe beneath the rostrum of corpus callosum to the parahippocampal gyrus and uncus of the temporal lobe.[2]

Neurons of the cingulum receive afferent fibers from the parts of the thalamus that are associated with the spinothalamic tract. This, in addition to the fact that the cingulum is a central structure in learning to correct mistakes, indicates that the cingulum is involved in appraisal of pain and reinforcement of behavior that reduces it.[3]

Cingulotomy, the surgical severing of the anterior cingulum, is a form of psychosurgery used to treat depression and OCD.

The cingulum was one of the earliest identified brain structures.

  1. ^ Bubb, EJ; Metzler-Baddeley, C; Aggleton, JP (September 2018). "The cingulum bundle: Anatomy, function, and dysfunction". Neuroscience and Biobehavioral Reviews. 92: 104–127. doi:10.1016/j.neubiorev.2018.05.008. PMC 6090091. PMID 29753752.
  2. ^ J. Edward Bruni, Donald Montemurro, Human Neuroanatomy: A Text, Brain Atlas and Laboratory Dissection Guide, Oxford University Press, 2009[full citation needed]
  3. ^ Per Brodal: The Central Nervous System[full citation needed]