Cismadinone

Cismadinone
Clinical data
Other names	6α-Chloro-1,2-didehydro-17α-hydroxyprogesterone
Identifiers
	IUPAC name (1S,2R,8S,10R,11S,14R,15S)-14-acetyl-8-chloro-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one;
CAS Number	54063-31-9;
PubChem CID	193990;
ChemSpider	168332;
UNII	O00XM1O6TV;
CompTox Dashboard (EPA)	DTXSID10968900 ;
Chemical and physical data
Formula	C21H27ClO3
Molar mass	362.89 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)C1(CCC2C1(CCC3C2CC(C4=CC(=O)C=CC34C)Cl)C)O;
	InChI InChI=1S/C21H27ClO3/c1-12(23)21(25)9-6-16-14-11-18(22)17-10-13(24)4-7-19(17,2)15(14)5-8-20(16,21)3/h4,7,10,14-16,18,25H,5-6,8-9,11H2,1-3H3/t14-,15+,16+,18+,19-,20+,21+/m1/s1; Key:RNSISAJHBSCDGC-SCUQKFFVSA-N;

Cismadinone (INN), also known as 6α-chloro-17α-hydroxypregna-1,4-diene-3,20-dione or 6α-chloro-δ¹-dehydro-17α-hydroxyprogesterone, is a steroidal progestin closely related to the 17α-hydroxyprogesterone derivatives that was never marketed.^[1]^[2] An acetylated form, cismadinone acetate, also exists, but similarly to cismadinone, was never marketed.^[1]

^ ^a ^b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 284. ISBN 978-1-4757-2085-3.
^ World Health Organization (2013), The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF), p. 104, archived from the original (PDF) on August 8, 2016

[Elks2014-1] Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 284. ISBN 978-1-4757-2085-3.

[WHOINNStems2013-2] World Health Organization (2013), The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF), p. 104, archived from the original (PDF) on August 8, 2016

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