Cismadinone acetate

Not to be confused with Chlormadinone acetate.
Cismadinone acetate
Clinical data
Other names6α-chloro-δ1-dehydro-17α-acetoxyprogesterone; 6α-Chloro-1,2-didehydro-17α-acetoxyprogesterone; 6α-Chloro-17α-acetoxypregna-1,4-diene-3,20-dione
Drug classProgestogen; Progestogen ester
Identifiers
  • (1S,2R,8S,10R,11S,14R,15S)-14-acetyl-8-chloro-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl acetate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H29ClO4
Molar mass404.93 g·mol−1
3D model (JSmol)
  • CC(=O)C1(CCC2C1(CCC3C2CC(C4=CC(=O)C=CC34C)Cl)C)OC(=O)C
  • InChI=1S/C23H29ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h5,8,11,16-18,20H,6-7,9-10,12H2,1-4H3/t16-,17+,18+,20+,21-,22+,23+/m1/s1
  • Key:AQDNTKZTMCWYDA-WXLIAARGSA-N

Cismadinone acetate, also known as 6α-chloro-δ1-dehydro-17α-acetoxyprogesterone or as 6α-chloro-17α-acetoxypregna-1,4-diene-3,20-dione, is a steroidal progestin related to the 17α-hydroxyprogesterone derivatives which was never marketed.[1] It is the acetylated form of cismadinone, which is also a progestin but, similarly to cismadinone acetate, was never marketed.[2]

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 284. ISBN 978-1-4757-2085-3.
  2. ^ World Health Organization (2013), The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF), p. 104, archived from the original (PDF) on August 8, 2016