| Cities of regional significance | |
|---|---|
&sq=&lang=&file=File:Ukraine_raions.png) The cities are marked with Latin alphabet lettering. | |
| Category | Second-level subdivision |
| Location |  Ukraine |
| Created |
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| Abolished |
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| Number | 182 (as of 2015) |
| Government |
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| Subdivisions |
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A city of regional significance (Ukrainian: місто обласного значення, romanized: misto oblasnoho znachennia) in Ukraine was a type of second-level administrative division or municipality, the other type being raions (districts). In the first-level division of oblasts, they were referred to as cities of oblast significance; in the first-level autonomous republic of Crimea, they were cities of republican significance. The designation was created with the introduction of oblasts in 1932. It was abolished in a 2020 reform that merged raions together and integrated the city municipalities into them.
Such city municipality was complex and usually combined the city proper and adjacent populated places. The city of regional (oblast) significance was governed by a city council known as mis'krada, which was chaired by a mayor. There were instances where a municipality might have included only the city alone (city proper), while in others instances a municipality might have consisted of its own subdivisions such as districts in city, similarly to the cities with special status or even other cities which carried the designation of cities of district significance.