| Clear-cell adenocarcinoma | |
|---|---|
 | |
| Micrograph of an ovarian clear-cell adenocarcinoma. H&E stain | |
| Specialty | Oncology  |
Clear-cell adenocarcinoma is a rare and aggressive form of cancer that typically arises in the female reproductive organs, particularly the ovaries and the endometrium as well as the kidneys and is characterized by the presence of clear,[1] glycogen-rich cells.[2] Specific criteria must be met for a tumor to be classified as clear cell adenocarcinoma. According to the WHO, these criteria include polygonal or hobnail or cells with clear or eosinophilic/oxyphilic cytoplasm and nuclear atypia, with different architectural patterns of growth, such as papillary, tubulocystic, or solid.[1]
- ^ a b "NCI Dictionary of Cancer Terms". National Cancer Institute. 2 February 2011. Retrieved 10 July 2019.
- ^ Guo Y, Shrestha A, Maskey N, Dong X, Zheng Z, Yang F, et al. (2022). "Recent Trends in the Incidence of Clear Cell Adenocarcinoma and Survival Outcomes: A SEER Analysis". Frontiers in Endocrinology. 13: 762589. doi:10.3389/fendo.2022.762589. PMC 8907425. PMID 35282450.