Clenbuterol

Clenbuterol
Clenbuterol (top),
and (R)-(−)-clenbuterol (bottom)
Clinical data
Trade namesDilaterol, Spiropent, Ventipulmin, others[1]
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • C
Routes of
administration		Oral (tablets, oral solution)
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only
Pharmacokinetic data
Bioavailability89–98% (orally)
MetabolismHepatic (negligible)
Elimination half-life36–48 hours
ExcretionFeces and urine
Identifiers
  • (RS)-1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethan-1-ol
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.048.499 Edit this at Wikidata
Chemical and physical data
FormulaC12H18Cl2N2O
Molar mass277.19 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • Clc1cc(cc(Cl)c1N)C(O)CNC(C)(C)C
  • InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3 checkY
  • Key:STJMRWALKKWQGH-UHFFFAOYSA-N checkY
  (verify)

Clenbuterol is a sympathomimetic amine used by sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this as a bronchodilator to make breathing easier. It is most commonly available as the hydrochloride salt, clenbuterol hydrochloride.[2]

It was patented in 1967 and came into medical use in 1977.[3]

  1. ^ Center for Veterinary Medicine. "FOIA Drug Summaries - NADA 140-973 VENTIPULMIN® SYRUP - original approval". www.fda.gov. Retrieved 2016-03-10.
  2. ^ "874. Clenbuterol (WHO Food Additives Series 38)". www.inchem.org. Retrieved 2016-03-10.
  3. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 543. ISBN 978-3-527-60749-5.