Clostridium novyi

Clostridium novyi
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Bacillota
Class: Clostridia
Order: Eubacteriales
Family: Clostridiaceae
Genus: Clostridium
Species:
C. novyi
Binomial name
Clostridium novyi
(Migula 1894 [sic]) Bergey et al. 1923[1]

Clostridium novyi (oedematiens) a Gram-positive, endospore- forming, obligate anaerobic bacteria of the class Clostridia. It is ubiquitous, being found in the soil and faeces. It is pathogenic, causing a wide variety of diseases in humans and animals.

Growth in culture proceeds through 3 stages: Initial growth wherein no toxin is produced; vigorous growth wherein toxin is produced; and spore formation wherein endospores are formed and toxin production decreases. It is suggested that type C may be type B that forms spores more readily so does not go through the toxin-production stage.

Isolating and identifying C novyi is difficult due to its extreme anaerobic nature. Commercial kits may not be adequate.[2][3]

It is also fastidious and difficult to culture, requiring the presence of thiols.[4]

  1. ^ Parte, A.C. "Clostridium". LPSN.
  2. ^ Brazier JS, Duerden BI, Hall V, et al. (November 2002). "Isolation and identification of Clostridium spp. from infections associated with the injection of drugs: experiences of a microbiological investigation team". Journal of Medical Microbiology. 51 (11): 985–9. doi:10.1099/0022-1317-51-11-985. PMID 12448683.
  3. ^ "Identification of Clostridium species". National Standard Methods (PDF). BSOP ID8 Issue 3. Health Protection Agency. July 2008. Archived from the original (PDF) on 2009-11-05. Retrieved 2010-02-26.
  4. ^ Moore WB (October 1968). "Solidified media suitable for the cultivation of Clostridium novyi type B". Journal of General Microbiology. 53 (3): 415–23. doi:10.1099/00221287-53-3-415. PMID 5721591.