Clustal

CLUSTAL
Developer(s)
  • Des Higgins
  • Fabian Sievers
  • David Dineen
  • Andreas Wilm (all at the Conway Institute, UCD)
Stable release
1.2.2 / 1 July 2016; 8 years ago (2016-07-01)
Written inC++
Operating systemUNIX, Linux, MacOS, MS-Windows, FreeBSD, Debian
TypeBioinformatics tool
LicenceGNU General Public License, version 2[1]
Websitewww.clustal.org/omega/

Clustal is a computer program used for multiple sequence alignment in bioinformatics.[2] The software and its algorithms have gone through several iterations, with ClustalΩ (Omega) being the latest version as of 2011. It is available as standalone software, via a web interface, and through a server hosted by the European Bioinformatics Institute.

Clustal has been an important bioinformatic software, with two of its academic publications amongst the top 100 papers cited of all time, according to Nature in 2014.[3]

Multiple sequence alignment of CDK4 protein generated with ClustalW. Arrows indicate point mutations.
  1. ^ See file COPYING, in source archive [1] Archived 2021-06-12 at the Wayback Machine. Accessed 2014-01-15.
  2. ^ Chenna R, Sugawara H, Koike T, Lopez R, Gibson TJ, Higgins DG, Thompson JD (July 2003). "Multiple sequence alignment with the Clustal series of programs". Nucleic Acids Research. 31 (13): 3497–500. doi:10.1093/nar/gkg500. PMC 168907. PMID 12824352.
  3. ^ Van Noorden R, Maher B, Nuzzo R (October 2014). "The top 100 papers". Nature. 514 (7524): 550–3. Bibcode:2014Natur.514..550V. doi:10.1038/514550a. PMID 25355343.