Concentrative nucleoside transporter 1

SLC28A1
Identifiers
Aliases	SLC28A1, CNT1, HCNT1, Concentrative nucleoside transporter 1, solute carrier family 28 member 1, URCTU
External IDs	OMIM: 606207; MGI: 3605073; HomoloGene: 37902; GeneCards: SLC28A1; OMA:SLC28A1 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	84,945,798 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	80,820,164 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; testicle; ; human kidney; ; duodenum; ; mucosa of ileum; ; jejunal mucosa; ; kidney tubule; ; muscle of thigh; ; apex of heart; ; renal medulla;
	Top expressed in
	proximal tubule; ; duodenum; ; right kidney; ; human kidney; ; neck; ; pharynx; ; embryo; ; primary oocyte; ; bone marrow; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleoside transmembrane transporter activity; pyrimidine- and adenine-specific:sodium symporter activity; nucleoside:sodium symporter activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	pyrimidine nucleobase transport; nucleoside transport; pyrimidine-containing compound transmembrane transport; nucleoside transmembrane transport; nucleobase-containing compound metabolic process; purine nucleobase transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	9154
	434203
	ENSG00000156222
	ENSMUSG00000025726
	O00337
	E9PXX9
NM_001287761; NM_001287762; NM_004213; NM_201651; NM_001321721;
	NM_001321722
	NM_001004184
NP_001274690; NP_001274691; NP_001308650; NP_001308651; NP_004204;
	NP_964014
	NP_001004184
	Wikidata
View/Edit Human	View/Edit Mouse

Concentrative nucleoside transporter 1 (CNT1) is a protein that in humans is encoded by the SLC28A1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156222 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025726 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ritzel MW, Yao SY, Huang MY, Elliott JF, Cass CE, Young JD (Apr 1997). "Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)". Am J Physiol. 272 (2 Pt 1): C707–14. doi:10.1152/ajpcell.1997.272.2.C707. PMID 9124315.
^ "Entrez Gene: SLC28A1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156222 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025726 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9124315-5] Ritzel MW, Yao SY, Huang MY, Elliott JF, Cass CE, Young JD (Apr 1997). "Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)". Am J Physiol. 272 (2 Pt 1): C707–14. doi:10.1152/ajpcell.1997.272.2.C707. PMID 9124315.

[entrez-6] "Entrez Gene: SLC28A1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1".

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