Congenital insensitivity to pain with anhidrosis

Congenital insensitivity to pain with anhidrosis
Charcot joints are shown in this boy with CIPA.
Causes	Genetic mutations

Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder of the nervous system which prevents the feeling of pain or temperature and prevents a person from sweating. Cognitive disorders are commonly coincidental. CIPA is the fourth type of hereditary sensory and autonomic neuropathy (HSAN), and is also known as HSAN IV.