Coomassie brilliant blue

Coomassie Brilliant Blue R-250
Skeletal formula of Coomassie brilliant blue R-250
Space-filling model of the coomassie brilliant blue R-250 molecule
Names
Other names
C.I. 42660, C.I. Acid Blue 83
Brilliant indocyanine 6B, Brillantindocyanin 6B
Brilliant Cyanine 6B, Serva Blue R
Identifiers
3D model (JSmol)
ECHA InfoCard 100.025.509 Edit this at Wikidata
UNII
  • CCN(CC1=CC(=CC=C1)S(=O)(=O)O)C2=CC=C(C=C2)C(=C3C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3)C5=CC=C(C=C5)NC6=CC=C(C=C6)OCC.[Na+]
Properties
C45H44N3NaO7S2 (Sodium salt)
Molar mass 825.97 g/mol
Insoluble in cold, slightly soluble in hot (bright red blue)
Solubility in ethanol Slightly soluble
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Coomassie brilliant blue G-250
Solid Coomassie brilliant blue G
Brilliant blue G in isopropanol solution
Names
Other names
C.I. 42655, C.I. Acid Blue 90
Brilliant indocyanine G, Brillantindocyanin G
Xylene Brilliant Cyanine G, Serva Blue G
Identifiers
3D model (JSmol)
ECHA InfoCard 100.025.509 Edit this at Wikidata
KEGG
  • CCN(CC1=CC(=CC=C1)S(=O)(=O)O)C2=CC(=C(C=C2)/C(=C\3/C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)O)C=C3C)/C5=CC=C(C=C5)NC6=CC=C(C=C6)OCC)C
Properties
C47H50N3NaO7S2 (Sodium salt)
Molar mass 856.03 g/mol
Slightly soluble in cold, soluble in hot (bright blue)
Solubility in ethanol Soluble
Pharmacology
Legal status
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Coomassie brilliant blue is the name of two similar triphenylmethane dyes that were developed for use in the textile industry but are now commonly used for staining proteins in analytical biochemistry. Coomassie brilliant blue G-250 differs from Coomassie brilliant blue R-250 by the addition of two methyl groups. The name "Coomassie" is a registered trademark of Imperial Chemical Industries.

  1. ^ "Health product highlights 2021: Annexes of products approved in 2021". Health Canada. 3 August 2022. Retrieved 25 March 2024.