Cross-city route

Melbourne tram route 96 is a cross-city route connecting two very different suburbs, East Brunswick and St Kilda.
Ashland/63rd CTA station is a terminus of the Green Line, the only through route to run around the Loop on the Chicago 'L' rapid transit system.

A cross-city route is a public transport route linking one suburb (or satellite) of a city or town with another, usually relatively distant, suburb (or satellite).

Such a route can be operated by various forms of public transport, including commuter rail, rapid transit, trams (streetcars), trolleybuses, or motor buses.