Cyclin A1

CCNA1
Identifiers
Aliases	CCNA1, CT146, Cyclin A1
External IDs	OMIM: 604036; MGI: 108042; HomoloGene: 31203; GeneCards: CCNA1; OMA:CCNA1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	36,442,870 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	54,962,922 bp
RNA expression pattern
	Top expressed in
	sperm; ; left testis; ; right testis; ; ventricular zone; ; right uterine tube; ; ganglionic eminence; ; testicle; ; middle temporal gyrus; ; prefrontal cortex; ; nucleus accumbens;
	Top expressed in
	spermatid; ; spermatocyte; ; seminiferous tubule; ; embryo; ; embryo; ; ventricular zone; ; left lung lobe; ; granulocyte; ; primary visual cortex; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein kinase activity; cyclin-dependent protein serine/threonine kinase regulator activity; protein kinase binding;
Cellular component	microtubule cytoskeleton; cytosol; nucleus; nucleoplasm; cyclin A1-CDK2 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cyclin A2-CDK2 complex;
Biological process	cell division; cell cycle; male meiosis I; regulation of transcription involved in G1/S transition of mitotic cell cycle; spermatogenesis; protein deubiquitination; regulation of cyclin-dependent protein serine/threonine kinase activity; mitotic cell cycle; protein phosphorylation; regulation of mitotic nuclear division; positive regulation of cell population proliferation; positive regulation of cell cycle; mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	8900
	12427
	ENSG00000133101
	ENSMUSG00000027793
	P78396
	Q61456
	NM_001111045; NM_001111046; NM_001111047; NM_003914
	NM_007628; NM_001305221
	NP_001104515; NP_001104516; NP_001104517; NP_003905
	NP_001292150; NP_031654
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000133101 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027793 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yang R, Morosetti R, Koeffler HP (March 1997). "Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines". Cancer Res. 57 (5): 913–920. PMID 9041194.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000133101 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027793 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9041194-5] Yang R, Morosetti R, Koeffler HP (March 1997). "Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines". Cancer Res. 57 (5): 913–920. PMID 9041194.

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