Cyclopia

Cyclopia
Other namesCyclocephaly, synophthalmia
Fetuses with cyclopia
SpecialtyMedical genetics
Usual onsetDuring embryonic development
DurationLifelong
PrognosisAlways fatal within a day
Frequency1 in 100,000 births

Cyclopia (named after the Greek mythology character cyclopes), also known as alobar holoprosencephaly, is the most extreme form of holoprosencephaly and is a congenital disorder (birth defect) characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses.[1][2]

  1. ^ Taber's Cyclopedic Medical Dictionary, ISBN 0-8036-0654-0
  2. ^ Leroi, Armand Marie Mutants: On Genetic Variety and the Human Body, p.73. ISBN 978-0142004821