DDB1

DDB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2B5L, 2B5M, 2B5N, 2HYE, 3E0C, 3EI1, 3EI2, 3EI3, 3EI4, 3I7H, 3I7K, 3I7L, 3I7N, 3I7O, 3I7P, 3I89, 3I8C, 3I8E, 4A08, 4A09, 4A0A, 4A0B, 4A0K, 4A0L, 4A11, 4CI1, 4CI2, 4CI3, 4E54, 4E5Z, 4TZ4, 5FQD, 5HXB
Identifiers
Aliases	DDB1, DDBA, UV-XAP1, XPCE, XPE, XPE-BF, damage specific DNA binding protein 1, WHIKERS
External IDs	OMIM: 600045; MGI: 1202384; HomoloGene: 1448; GeneCards: DDB1; OMA:DDB1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	61,342,596 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	10,607,183 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; ventricular zone; ; stromal cell of endometrium; ; right testis; ; ganglionic eminence; ; left testis; ; right uterine tube;
	Top expressed in
	Ileal epithelium; ; neural layer of retina; ; spermatocyte; ; choroid plexus of fourth ventricle; ; gastrula; ; ventricular zone; ; epiblast; ; tail of embryo; ; lactiferous gland; ; hand;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein binding; nucleic acid binding; damaged DNA binding; protein-macromolecule adaptor activity; cullin family protein binding; WD40-repeat domain binding; protein-containing complex binding;
Cellular component	cytoplasm; nucleoplasm; Cul4A-RING E3 ubiquitin ligase complex; Cul4B-RING E3 ubiquitin ligase complex; extracellular exosome; nucleus; extracellular space; Cul4-RING E3 ubiquitin ligase complex; protein-containing complex;
Biological process	regulation of mitotic cell cycle phase transition; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; positive regulation by virus of viral protein levels in host cell; histone H2A monoubiquitination; negative regulation of apoptotic process; Wnt signaling pathway; global genome nucleotide-excision repair; biological process involved in interaction with symbiont; positive regulation of viral genome replication; transcription-coupled nucleotide-excision repair; viral process; nucleotide-excision repair, DNA incision; UV-damage excision repair; DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, preincision complex stabilization; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, DNA incision, 5'-to lesion; post-translational protein modification; proteasomal protein catabolic process; cellular response to DNA damage stimulus; protein ubiquitination; positive regulation of protein catabolic process; ubiquitin-dependent protein catabolic process; regulation of circadian rhythm; positive regulation of gluconeogenesis; rhythmic process;
	Sources:Amigo / QuickGO
Orthologs
	1642
	13194
	ENSG00000167986
	ENSMUSG00000024740
	Q16531
	Q3U1J4
	NM_001923
	NM_015735
	NP_001914
	NP_056550
	Wikidata
View/Edit Human	View/Edit Mouse

DNA damage-binding protein 1 is a protein that in humans is encoded by the DDB1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167986 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024740 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cite error: The named reference pmid8530102 was invoked but never defined (see the help page).
^ Cite error: The named reference pmid10574459 was invoked but never defined (see the help page).
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167986 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024740 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8530102-5] Cite error: The named reference pmid8530102 was invoked but never defined (see the help page).

[pmid10574459-6] Cite error: The named reference pmid10574459 was invoked but never defined (see the help page).

[entrez-7] Cite error: The named reference entrez was invoked but never defined (see the help page).

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