DLX3

DLX3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4XRS
Identifiers
Aliases	DLX3, AI4, TDO, AV237891, Dlx-3, distal-less homeobox 3
External IDs	OMIM: 600525; MGI: 94903; HomoloGene: 74544; GeneCards: DLX3; OMA:DLX3 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	49,995,224 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	95,016,122 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; skin of arm; ; testicle; ; placenta; ; gums; ; gingival epithelium; ; skin of thigh; ; popliteal artery; ; tibial arteries;
	Top expressed in
	tooth; ; molar; ; lip; ; hair follicle; ; incisor; ; tongue; ; skin of back; ; lower jaw; ; genital tubercle; ; mandible;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; chromatin binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	multicellular organism development; regulation of transcription, DNA-templated; placenta development; blood vessel development; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; odontoblast differentiation; odontogenesis of dentin-containing tooth; regulation of transcription by RNA polymerase II; cell differentiation; epithelial cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	1747
	13393
	ENSG00000064195
	ENSMUSG00000001510
	O60479
	Q64205
	NM_005220
	NM_010055
	NP_005211
	NP_034185
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein DLX-3 is a protein that in humans is encoded by the DLX3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000064195 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001510 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Scherer SW, Heng HH, Robinson GW, Mahon KA, Evans JP, Tsui LC (Aug 1995). "Assignment of the human homolog of mouse Dlx3 to chromosome 17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in situ hybridization". Mamm Genome. 6 (4): 310–1. doi:10.1007/BF00352432. PMID 7613049. S2CID 3088522.
^ "Entrez Gene: DLX3 distal-less homeobox 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000064195 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000001510 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7613049-5] Scherer SW, Heng HH, Robinson GW, Mahon KA, Evans JP, Tsui LC (Aug 1995). "Assignment of the human homolog of mouse Dlx3 to chromosome 17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in situ hybridization". Mamm Genome. 6 (4): 310–1. doi:10.1007/BF00352432. PMID 7613049. S2CID 3088522.

[entrez-6] "Entrez Gene: DLX3 distal-less homeobox 3".

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