DUF3577 RNA motif

This article relies excessively on references to primary sources. Please improve this article by adding secondary or tertiary sources. Find sources: "DUF3577 RNA motif" – news · newspapers · books · scholar · JSTOR (November 2021) (Learn how and when to remove this message)

DUF3577
Consensus secondary structure and sequence conservation of DUF3577 RNA
Identifiers
Symbol	DUF3577
Rfam	RF02954
Other data
RNA type	Cis-reg
SO	SO:0005836
PDB structures	PDBe

The DUF3577 RNA motif is a conserved RNA structure that was discovered by bioinformatics.^[1] DUF3577 motifs are found in the organism Cardiobacterium valvarum and metagenomic sequences from unknown organisms.

DUF3577 motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. Most of these genes are not classified as encoding conserved protein domains. However, some encode the DUF3577 or DUF39 domain. The functions of these domains are not known. Many DUF3577 RNAs are located 5′ to Rho-independent transcription terminators, which, in turn, are 5′ to the start codon of the downstream gene. These transcription terminators could play a role in the regulatory function of the RNA, although transcription terminators are also often found 3′ to small RNAs that are transcribed independently from downstream genes.