David Mills may refer to:
- David Mills (author) (born 1959), American author
- David Mills (bass) (1926–2020), Canadian singer, poet. composer, actor
- David Mills (Canadian politician) (1831–1903), Canadian politician and Supreme Court judge
- David Mills (comedian) (living), London-based American comedy actor and cabaret artist
- David Mills (cricketer) (1937–2013), English cricketer
- David Mills (editor) (born 1957), American editor and writer
- David Mills (footballer) (born 1951), English footballer and scout
- David Mills (solicitor) (born 1944), British lawyer
- David Mills (rugby league) (born 1981), English rugby league footballer
- David Mills (solar researcher) (born 1946), Australian scientist
- David Mills (TV writer) (1961–2010), American journalist and TV writer
- David L. Mills (1938–2024), American academic computer engineer
- David P. Mills, British chemist
- Detective David Mills, a fictional character in the 1995 film Seven
- Dave Mills (singer), South African singer
- Gyp Mills (David John Mills, 1946–2019), sculptor and songwriter