David Patterson may refer to:
- David Patterson (computer scientist) (born 1947), American professor of computer science at UC Berkeley
- Dave Patterson (born 1956), American baseball player
- David Patterson (guitarist) (born 1966), American guitarist who was a founding member of the New World Guitar Trio
- David Patterson (American football) (born 1985), defensive lineman for the Ohio State Buckeyes and the Atlanta Falcons
- David J. Patterson (born 1950), Irish biologist
- David P. Patterson (c.1840–1879), director of New Jersey and New York Railroad, and a town father of Hillsdale, New Jersey
- David T. Patterson (1818–1891), American politician; Democrat from Tennessee; in U.S. Senate 1866–69
- David Allen Patterson, professor, researcher, author and Native American advocate
- David Patterson (historian), who mainly researches the Holocaust, Jewish thought, and antisemitism