Death receptor 5

TNFRSF10B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, tumor necrosis factor receptor superfamily member 10b, TNF receptor superfamily member 10b
External IDsOMIM: 603612; MGI: 1341090; HomoloGene: 117702; GeneCards: TNFRSF10B; OMA:TNFRSF10B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003842
NM_147187

NM_020275

RefSeq (protein)

NP_003833
NP_671716

NP_064671

Location (UCSC)Chr 8: 23.02 – 23.07 MbChr 14: 70 – 70.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Death receptor 5 (DR5), also known as TRAIL receptor 2 (TRAILR2) and tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), is a cell surface receptor of the TNF-receptor superfamily that binds TRAIL and mediates apoptosis.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120889Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022074Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.