Decoy receptor 3

TNFRSF6B
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesTNFRSF6B, DCR3, DJ583P15.1.1, M68, M68E, TR6, tumor necrosis factor receptor superfamily member 6b, TNF receptor superfamily member 6b
External IDsOMIM: 603361; HomoloGene: 48242; GeneCards: TNFRSF6B; OMA:TNFRSF6B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032945
NM_003823

n/a

RefSeq (protein)

NP_003814

n/a

Location (UCSC)Chr 20: 63.7 – 63.7 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-induced apoptosis.[3][4][5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000243509Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Pitti RM, Marsters SA, Lawrence DA, Roy M, Kischkel FC, Dowd P, Huang A, Donahue CJ, Sherwood SW, Baldwin DT, Godowski PJ, Wood WI, Gurney AL, Hillan KJ, Cohen RL, Goddard AD, Botstein D, Ashkenazi A (Jan 1999). "Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer". Nature. 396 (6712): 699–703. doi:10.1038/25387. PMID 9872321. S2CID 4427455.
  4. ^ Yu KY, Kwon B, Ni J, Zhai Y, Ebner R, Kwon BS (Jun 1999). "A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis". J Biol Chem. 274 (20): 13733–6. doi:10.1074/jbc.274.20.13733. PMID 10318773.
  5. ^ "Entrez Gene: TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy".